چکیده (انگلیسی):

Objectives: Current study is a comparative, prospective, randomized, short-term outcome study to compare the early results of Total Knee Arthroplasty in female patients using either standard or gender-specific knee prosthesis for treatment of advanced osteoarthritis of the knee joint. Background: Gender-specific knee athroplasty prosthesis is designed to better accommodate the differences noted in distal femoral anatomy in female patients compared to males. Several studies have reported differences in knee morphometry between genders such as the height/width ratio of the distal femoral condyle, the quadriceps angle and the shape of the distal femur. The need for Gender-specific (GS) femoral prostheses is still debated and has led us to compare short-term outcomes of TKA using standard (STD) or GS femoral components. Methods: In the period between February 2012 and February 2013, a comparative prospective randomized study was conducted involving 34 female patients with 40 knees who underwent primary total knee arthroplasty for knee joint advanced osteoarthritis and divided into two groups , The first group included 20 knees underwent total knee arthroplasty using Gender-Specific Knee Design with Gender-Specific femoral component (Zimmer Gender Solutions NexGen High-Flex ( NexGen LPS-Flex ) Implant , The second group included 20 knees underwent total knee arthroplasty using standard Knee Design with Standard femoral component (Zimmer NexGen LPS Implant). Results: No statistically significant differences were observed between the two groups regarding pain improvement, range of motion improvement, pre and post operative OXFORD scores, Knee Society Scores, WOMAC scores, satisfaction, preference, complications, and radiographic results. Conclusion: Early clinical outcomes for the knees with a gender-specific NexGen LPS-Flex prosthesis were similar to those for the knees with a standard NexGen LPS prosthesis in female patients. gender-specific knee prosthesis showed no advantages over standard unisex knee prosthesis in terms of early clinical outcomes.