تحقیق و توسعه در موردآنتی اکسیدان در پیشگیری از عوارض دیابت
The research and development on the antioxidants in prevention of diabetic complications
نویسندگان |
این بخش تنها برای اعضا قابل مشاهده است ورودعضویت |
اطلاعات مجله |
Asian Pacific Journal of Tropical Medicine 2016 |
سال انتشار |
2016 |
فرمت فایل |
PDF |
کد مقاله |
1719 |
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چکیده (انگلیسی):
Diabetes mellitus can damage the eyes, kidneys, nerves and heart. Microvascular and
macrovascular disorders are the leading causes of morbidity and mortality in diabetic
patients. Hyperglycemia can increase the indicators of lipid peroxidation and oxidative
stress in which free radicals have the main role in the pathogenesis of these complications.
Therefore, antioxidants which combat oxidative stress should be able to prevent
and repair free radicals induced damages. Although free radicals contribute to kidney
damage, atherosclerosis, diabetes, heart disease, nephrotoxicity and hepatotoxicity;
however, clinical trials do not uniquely confirm a substantial impact on diabetic damage.
It seems that antioxidants in vegetables, fruits and grains help preventing diabetes
complications; however, there is little evidence that taking single antioxidants such as
vitamin E or vitamin C protect these complications. The findings about combination
antioxidants are also complicated and not entirely clear. In this review paper we tried to
present the role of oxidative stress on micro-vascular complications of type 2 diabetes
mellitus. Other objective of this paper is to review the new findings about the role of
various antioxidants on prevention and treatment of diabetes mellitus as well as its
complications including retinopathy, nephropathy and neuropathy.
کلمات کلیدی مقاله (فارسی):
نفروپاتی -دیابتی -آنتی اکسیدان های طبیعی -عوارض دیابت -نفروپاتی -نوروپاتی -رتینوپاتی
کلمات کلیدی مقاله (انگلیسی):
Diabetic nephropathy Natural antioxidants Diabetes complications Nephropathy Neuropathy Retinopathy
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