چکیده (انگلیسی):

: Outcomes following Coronary artery bypass grafting (GABG) vary between genders, with
females having a higher postoperative mortality than males. Most of the studies are on Caucasian or
mixed population and it is postulated that Asian population and in particular women have higher
morbidity and mortality. In this study we have compared outcomes of elective CABG in men and women
of South Asian origin in terms of morbidity and mortality.
Methods: From January 2006 to December 2012, 1970 patients underwent isolated elective CABG at the
Aga Khan University Hospital, Pakistan were selected. The prospectively collected data was analyzed
retrospectively including univariate and multivariate analysis to find the association of morbidity and
mortality.
Results: Among the study patients 1664 (85%) were male and 306 (15%) female. Hypertension and
diabetes were the most common comorbid conditions seen preoperatively in female patients. Atrial
fibrillation and sepsis were the most common postop complications seen in females. In hospital mortality
was 3.9% in female underwent CABG as against 0.6% in male. Multivariate analysis showed older
age, renal failure, dyslipidemia and prolonged cross clamp time as predictors of postoperative morbidity.
Multivariate analysis showed female gender, age and renal failure as predictors of in hospital mortality.
Conclusions: Female gender is an independent risk factor for postoperative mortality following CABG
however, female gender is not found to be independent risk factor for morbidity. The trend of higher
mortality in female patients was comparable to most studies done on Caucasian patients