چکیده (انگلیسی):

It is time to bring our imagination, creativity and passion to the fore in solving the global challenges of our age.
Our global health crisis and the pandemic of noncommunicable diseases (NCDs) is clearly rooted in complex
modern societal and environmental changes, many of which have effects on developing immune and metabolic
responses. It is intimately related to wider environmental challenges. And it is unsurprising that many NCDs
share similar risk factors and that many are associated with a rising predisposition for inflammation. Allergy is
one of the earliest signs of environmental impact on these biological pathways, and may also offer an early barometer
to assess the effects of early interventions. There is dawning awareness of how changing microbial diversity,
nutritional patterns, sedentary indoor behaviours and modern pollutants adversely affect early metabolic
and immune development, but still much to understand the complexity of these interactions. Even when
we do harness the science and technology, these will not provide solutions unless we also address the wider
social, cultural and economic determinants of health - addressing the interconnections between human health
and the health of our environment. Now more than ever, we need a wider vision and a greater sense of collective
responsibility. We need long-range approaches that aim for life long benefits of a ‘healthier start to life’, and
stronger cross-sectoral collaborations to prevent disease. We need to give both our hearts and our minds to
solving these global issues.