چکیده (انگلیسی):

Objective: The study presents a matched-pair analysis of robot-assisted laparoscopic
partial nephrectomy (RALPN) versus radiofrequency ablation (RFA) to compare the perioperative
incidence of complications and chronic kidney disease (CKD).
Methods: All 46 RFA and 206 RALPN cases from June 2005 to December 2011 were retrospectively
reviewed from the medical records and were matched 1:1 based on propensity scores
by sex, tumor size, tumor laterality of kidney, tumor location within the kidney, and clinical
T stage. Hilar vessel clamping was performed in all RALPN patients. The estimated glomerular
filtration rate was used to define the CKD of < 60 mL/minute/1.73 m2 by the Modification of Diet
in Renal Disease equation. All patients with baseline CKD or solitary kidney were excluded prior
to the matching analysis. The complication was noted with modified Clavien grades
3. Statistical
analysis was performed to compare the perioperative incidence of complications and CKD.
Results: A total of 27 matched pairs of RFA and RALPN patients were enrolled for analyzing CKD
and perioperative complications. The better general conditions, higher estimated blood loss and transfusion rates, and longer operative time and hospital stay were observed significantly in
RALPN patients (p < 0.05). Matched analysis demonstrated that the incidences of both perioperative
complications (p Z 0.434) and of CKD (p Z 0.500) were not significantly different. No
complication higher than Grade 4 was detected in either group.
Conclusion: Despite the intraoperative renal ischemia and invasiveness of the procedure associated
with RALPN, the incidence of perioperative complication and of CKD developing rates were
statistically similar.