چکیده (انگلیسی):

Background: Thyroid nodules are commonly encountered problems in clinical practice. For patients who
have a thyroid nodule, the fine-needle aspiration biopsy (FNAB) is the most important test, as it is the
most reliable diagnostic method for distinguishing between benign thyroid nodules and cancerous
nodules. FNAB is able to be performed either via an ultrasound (USG) or alone and is the first choice
when it comes to diagnosing thyroid nodules, given that it is cheap, safe and provides accurate results.
Objective: In this study-a retrospective analysis of FNAB via USG - our aim is to evaluate the multiple
variables related to FNAB procedures, including the experience of the person performing the biopsy, the
age and gender of the patient, the number of nodules, the size of the nodule(s) and the number of lams
recorded from the cytopathology report on non-diagnostic rates, conducted at an invasive radiology
clinic and at a general surgery clinic.
Materials and methods: A total of 1062 patients involving 1869 nodules, examined using FNAB via USG,
were reviewed retrospectively from records dated between November 2011 and July 2014 and from
pathology reports taken from the ANEAH General Surgery clinic and Interventional Radiology clinic.
Cytopathology results were classified according to the 2007 Bethesda System for Reporting. Gender, age,
number of nodules, diameter of the nodules, biopsied nodules, location of the nodules, number of lams,
symptoms and the date of biopsies were the parameters used to examine the factors involved in nondiagnostic
cytopathology invasive radiology. These parameters were inspected at both of the clinics
(ANEAH General Surgery clinic and Interventional Radiology clinic). In analyzing the results, the statistical
significance level was set at 0.05, where in cases that the p value was under 0.05 (p < 0.05), it was
determined that no significant relationship existed. In this study, data were analyzed using SPSS 20
software.
Results: Of the nodules reviewed, 1620 were found on females and 249 on males. The age of the patients
ranged from 10 to 87 years, with the mean age being 50 years. In the general surgery clinic, 470 nodules
of 341 patients were aspirated, and in the interventional radiological clinic, 1399 nodules of 721 patients
were aspirated. In the literature review conducted to compare statistical assessments of FNAB via USG, no
significant difference was found between the ANEAH General Surgery clinic and the Invasive Radiology clinic (p > 0.05). In the invasive radiology clinic, non-diagnostic rates decreased with the increase in
experience of the person who conducted the biopsy (p ¼ 0.001).
Conclusion: The results from both of the clinic's rates of non-diagnostic FNAB, performed via USG, were
found to be acceptable. Our study also demonstrates that USG-guided FNAB can be performed with a low
non-diagnostic rate as experience grows.