چکیده (انگلیسی):

Background: The forced oscillation technique (FOT) is useful for studying pulmonary function in children, as
well as in school children with asthma. However, the standard values for respiratory resistance (Rrs) in Asian
school children remain unknown. We evaluated the standard Rrs using a type of FOT, impulse oscillometry
(IOS), in healthy Japanese children at elementary and junior high schools.
Methods: A total of 795 children (age range: 6-15 years; mean age ± SD: 11.1 ± 2.4 years; 404 boys, 391
girls) at elementary and junior high schools participated in the study. Of the 795 children, we evaluated the Rrs
of 537 children aged 6-15 years (mean ± SD: 10.8 ± 2.4 years) using IOS.
Results: Regression analyses with three IOS parameters, Rrs at 5 Hz (R5), Rrs at 20 Hz (R20), and Rrs difference
between 5 Hz and 20 Hz (R5-R20), for age, height, weight, and degree of obesity as independent variables
demonstrated the strongest correlation between each parameter and children’s height. All parameters
decreased with increasing height. Using the lambda-mu-sigma (LMS) method, we created standard curves for
the Rrs values based on height.
Conclusions: Our standard curves could be useful for diagnosis and control evaluation of childhood asthma.