چکیده (انگلیسی):

Clinical trials present an ethical dilemma for pharmaceutical companies. While companies may want to undertake
and report these trials in an ethical manner, negative results can significantly affect product sales. There is
accumulating evidence that company-financed trials are biased in favor of the product that the company makes.
Ethical conduct in this article is defined as whether the trials are conducted in the best interests of the participants
and/or reported in the best interests of patients. Nine examples of how clinical trials are violating multiple articles in
the Declaration of Helsinki are discussed using concrete case reports from the literature. The recognition of ethical
problems in company run trials is not something new, but to date no meaningful action has been taken to resolve
this issue. What is necessary is to separate the financing of clinical trials from their conduct.