چکیده (انگلیسی):

Background: Acute mesenteric ischemia (AMI) is a potentially life-threatening condition
because of its diagnostic difficulty, operative challenges, and comorbidities a patient may
have. The aim of this study was to identify factors associated with adverse outcomes in patients with
AMI.
Methods: The hospital records and clinical data of all patients with AMI were reviewed for a recent
4-year period. Clinical outcomes and factors influencing mortality were analyzed.
Results: Included in the study were 104 patients (46 females and 58males) with an overall mean age
of 66
13.4 years. The cause of AMI was arterial pathology in 74 (71%) patients, venous thrombosis in
15 (14%) patients, and nonocclusive ischemia in 12 (12%) patients. Abdominal pain was the most
common presenting symptom (97% of patients). The 30-day mortality rate was 66%. Univariate analysis
showed that mortality was associated with renal insufficiency (p Z 0.004), an age greater than
70 years (p Z 0.02), the presence of comorbidities (p Z 0.001), a leukocyte count greater than
18,000/mL (p Z 0.04), and small bowel necrosis of more than 100 cm (p < 0.0001). Logistic regression
analysis showed that independent predictors of mortality were small bowel necrosis of more
than 100 cm (p Z 0.002) and a serum creatinine level greater than 2 mg/dL (p Z 0.04).
Conclusion: The length of the necrosis and renal insufficiency are the primary factors that result in a
poor outcome in AMI patients. Prompt diagnostic evaluation and early therapeutic interventions
may help to prevent the development of these fatal predictors.