چکیده (انگلیسی):

Background/objective: One thousand liver transplantations have been performed
at the only liver transplant center in Hong Kong over a period of 22 years, which covered the
formative period of living donor liver transplantation. These 1000 transplantations, which
marked the journey of liver transplantation from development to maturation at the center,
should be educational. This research was to study the experience and to reflect on the importance
of technical innovations and case selection.
Methods: The first 1000 liver transplantations were studied. Key technical innovations and surgical
therapeutics were described. Recipient survival including hospital mortality was
analyzed. Recipient survival comparison was made for deceased donor liver transplantation
and living donor liver transplantation indicated by hepatocellular carcinoma and other diseases.
Results: Among the 1000 transplantations, 418 used deceased donor grafts and 582 used living
donor grafts. With the accumulation of experience, hospital mortality improved to < 2% in the
past 2 years. In the treatment of diseases other than hepatocellular carcinoma, living donor
liver transplantation was superior to deceased donor liver transplantation, with a 10-year
recipient survival around 90%.
Conclusion: Transplant outcomes have been improving consistently over the series, with a very
low hospital mortality and a predictably high long-term survival.