چکیده (انگلیسی):

Background: There are scarce data about the prevalence of Hymenoptera venom allergy in the general
population. The aim of this study was to determine the prevalence of Hymenoptera venom allergy in the
general adult population of Istanbul.
Methods: A total of 17,064 randomly selected telephone numbers were contacted and 11,816 (69.25%)
individuals who agreed to participate completed a questionnaire. Those who disclosed hypersensitivity
reactions due to Hymenoptera stings in this initial survey were called again and given another questionnaire.
Those who were suspected of experiencing hypersensitivity reactions to Hymenoptera stings
were invited for a clinical investigation with in vivo and in vitro diagnostic tests.
Results: According to the first questionnaire, a total of 1171 (9.9%; 95% CI: 9.38e10.47%) were suspected
of having a hypersensitivity to Hymenoptera stings. 51.75% (n: 606) answered the second questionnaire
and 21% (n: 128) of these were still suspected of having a hypersensitivity to Hymenoptera stings (1.1%;
95% CI: 0.9e1.29%). The confirmed prevalence of hypersensitivity to Hymenoptera stings according to
skin tests and in vitro sIgE levels was 0.2% (95% CI: 0.14e0.30%). Nearly all of the participants with
systemic reactions were admitted to the emergency department, although only one tenth of them
received adrenaline in the emergency room. 2.3% carried an adrenaline injector, whereas none of the
patients received venom immunotherapy.
Conclusions: The prevalence of Hymenoptera sting reactions in our geographical region is comparable
with other European studies. There is a need to increase the awareness of adrenaline in the emergency
management of insect sting anaphylaxis and venom immunotherapy in the prophylaxis.