چکیده (انگلیسی):

Objective: To determine the intermediate and long-term survival of patients diagnosed with colorectal
cancer (CRC) and to determine factors that affect survival.
Method: Patients were identified from a prospectively maintained colonoscopy database. All patients
who underwent colonoscopy during the period January 2008 to December 2012 and had histologically
confirmed invasive carcinoma were included. These patients were contacted at the end of 2013 to
determine their survival status. In addition to demographics, variables analyzed included presenting
complaint and tumor site and stage at presentation.
Results: Of 1757 patients being subjected to colonoscopy, 118 had endoscopic and histologic documentation
of invasive CRC. Of these the survival status of 102 was determined as of December 2013 and they
formed the basis of our study. The mean age of the group was 62 years with approximately 20% of the
group being age 50 years or younger. Females (54%) slightly outnumbered males. Anemia or overt rectal
bleeding was a dominant indication (44%) and 65% of the tumours were left sided. There were 58 (57%)
deaths and the median overall survival time was two years post diagnosis. Log rank tests for equality of
survivorship looking at age, gender, tumor site and presentation revealed that only presenting complaint
was a predictor of survivorship (p < 0.001). Patients presenting with bleeding or anemia have the best
survival.
Conclusions: Long-term survival from colorectal cancer remains poor with only about 33% of patients
being alive five years after their diagnosis.