رضایت درمان با کنترل آسم کودکان بهبود یافته : مطالعه آینده نگر برای تک درمانی بودزونید در کودکان از سن مدرسه با علائم آسم تحت کنترل
Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms
نویسندگان |
این بخش تنها برای اعضا قابل مشاهده است ورودعضویت |
اطلاعات مجله |
Allergology International http://www.journals.elsevier.com/allergology-international |
سال انتشار |
2015 |
فرمت فایل |
PDF |
کد مقاله |
7769 |
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چکیده (انگلیسی):
Background: If asthmatic children cannot obtain sufficient control of their disease, not only do they suffer
from asthma symptoms, but the daily life activities of their caregivers are also disrupted.We investigated
the effectiveness of an inhaled corticosteroid (ICS) for symptom control in previously ICS-untreated
school-aged asthmatic children as well as caregiver treatment satisfaction (CTS).
Methods: A multicenter, open-label, single-arm study on 12-week ICS (budesonide Turbuhaler®) monotherapy
was undertaken in subjects aged 5e15 years with bronchial asthma not treated with ICS during
the previous 3 months. At 0, 4, 8, and 12 weeks after start of ICS administration, Japanese Pediatric
Asthma Control Program (JPAC) scores, and CTS scores were summated and lung function measured. At
weeks 0 and 12, questionnaires on caregiver anxiety were also assessed.
Results: Seventy-five patients were enrolled, and 69 assessed. Ninety percent of subjects had been
treated with asthma controller medication except ICS before study enrollment. JPAC score and CTS score
were improved significantly at weeks 4, 8, and 12 (p < 0.001). With regard to CTS, more than half of
caregivers showed a perfect score at weeks 8 and 12. There was a significant correlation between JPAC
score and CTS score. Lung function and caregiver anxiety were also improved, and good compliance with
treatment was observed during the intervention.
Conclusions: If treating ICS-untreated school-aged asthmatic children with uncontrolled symptoms, ICS
monotherapy can improve CTS along with improving asthma control.
کلمات کلیدی مقاله (فارسی):
علائم آسم- تک درمانی بودزونید- مراقب رضایت درمان- JPAC-آسم کودکان
کلمات کلیدی مقاله (انگلیسی):
Asthma symptoms -Budesonide monotherapy -Caregiver treatment satisfaction- JPAC- Pediatric asthma
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