چکیده (انگلیسی):

Food allergy has grown in rapidly in prevalence, currently affecting 5% of adults and 8% of children.
Management strategy is currently limited to 1) food avoidance and 2) carrying and using rescue intramuscular
epinephrine/adrenaline and oral antihistamines in the case of accidental ingestion; there is no
FDA approved treatment. Recently, oral, sublingual and epicutaneous immunotherapy have been
developed as active treatment of food allergy, though none have completed phase 3 study. Efficacy and
safety studies of immunotherapy have been variable, though there is clearly signal that immunotherapy
will be a viable option to desensitize patients. The use of bacterial adjuvants, anti-IgE monoclonal antibodies,
and Chinese herbal formulations either alone or in addition to immunotherapy may hold
promise as future options for active treatment. Active prevention of food allergy through early introduction
of potentially offending foods in high-risk infants will be an important means to slow the rising
incidence of sensitization.
Copyright © 2016, Japanese Society of Allergology.