چکیده (انگلیسی):

Formal decision-analytic methods can be used to frame disease control problems, the first step of whichis to define a clear and specific objective. We demonstrate the imperative of framing clearly-definedmanagement objectives in finding optimal control actions for control of disease outbreaks. We illustratean analysis that can be applied rapidly at the start of an outbreak when there are multiple stakeholdersinvolved with potentially multiple objectives, and when there are also multiple disease models uponwhich to compare control actions. The output of our analysis frames subsequent discourse betweenpolicy-makers, modellers and other stakeholders, by highlighting areas of discord among different man-agement objectives and also among different models used in the analysis. We illustrate this approach inthe context of a hypothetical foot-and-mouth disease (FMD) outbreak in Cumbria, UK using outputs fromfive rigorously-studied simulation models of FMD spread. We present both relative rankings and rela-tive performance of controls within each model and across a range of objectives. Results illustrate howcontrol actions change across both the base metric used to measure management success and across thestatistic used to rank control actions according to said metric. This work represents a first step towardsreconciling the extensive modelling work on disease control problems with frameworks for structureddecision making.