چکیده (انگلیسی):

Background: Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollinosis (SAR-JCP) is a most common
allergic rhinitis, affecting about 40% in Japan, but the influence from SAR-JCP upon asthma is controversial.
The purpose of this study is to investigate the effect of coexistence of SAR-JCP upon control status
of asthma using SACRA (Self-Assessment of Allergic Rhinitis and Asthma Questionnaire).
Methods: The design was prospective, single-center, observational study. Asthmatic patients were classified
into 3 groups, patients without rhinitis, those with perennial rhinitis or those with SAR-JCP from
the results of SACRA. The control status of asthma were evaluated by Visual Analog Scale (VAS) in SACRA
and Asthma Control Test (ACT) score. They were evaluated twice, from September to January (nonpollenseason)
and February to April (pollen-season) and compared.
Results: 451 patients were enrolled and 325 cases (72%) were diagnosed as having comorbidity of
rhinitis, among which 173 with only perennial rhinitis, while 152 with SAR-JCP. There was no significant
difference in asthma control level measured by VAS and ACT score among 3 groups during nonpollenseason.
The asthma control level measured by VAS (1.91e2.95) and ACT score (22.7e21.6) got worse
during pollen-season among patients with SAR-JCP, even though 84% received treatment for rhinitis.
Although it differed according to criteria, asthma control during pollen-season was impaired in 18e38%
asthmatic patients with SAR-JCP.
Conclusion: It is possible to minimize the influence of AR on asthma control by obtaining an accurate
diagnosis and providing sufficient treatment for rhinitis.