ارزیابی سمیت ژنی برخی از نگهدارنده های غذایی رایج با استفاده از عصاره CEPA L. به عنوان یک گیاه آزمایشی
Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant
نویسندگان |
این بخش تنها برای اعضا قابل مشاهده است ورودعضویت |
اطلاعات مجله |
Toxicology Reports : www.elsevier.com/locate/toxrep |
سال انتشار |
2014 |
فرمت فایل |
PDF |
کد مقاله |
9222 |
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چکیده (انگلیسی):
Food preservatives play important role in today’s food supplies that are used to prolong
the self-life of products by protecting them from deterioration caused by micro-organisms.
In this study, investigations were carried out to study the impacts of food preservatives
like butylated hydroxytoluene, butylated hydroxyanisole, sorbic acid, propyl gallate and
sodium nitrate. The effects of these preservatives at concentration of 1000 ppm, 1500 ppm,
2000 ppm, 2500 ppm for 4 h, 8 h and 16 h of exposure period were studied on the root
tips of Allium cepa. Cytological studies revealed statistically significant (p < 0.05) inhibition
in mitotic index with an increase in concentration of the food preservatives when compared
with the control. Most frequent cytological abnormalities observed were bridges,
multipolarity, C-mitosis, stickiness and cell death. The total percentages of abnormalities
were also increased with increasing concentration and time duration. The abnormalities
(%) in root system caused by used preservatives were recorded as butylated hydroxytoluene
< butylated hydroxyanisole < sodium nitrate < sorbic acid < propyl gallate.
کلمات کلیدی مقاله (فارسی):
سمیت ژنی نگهدارنده غذا شاخص میتوزی اختلالات کروموزومی CEPA سیرها
کلمات کلیدی مقاله (انگلیسی):
Genotoxicity Food preservatives Mitotic index Chromosomal abnormalities Allium cepa
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