چکیده (انگلیسی):

Background: Asian dust (AD) has become a major health concern. The concentration of AD is typically
expressed in particulate matter less than 10 mm (PM10) and 2.5 mm (PM2.5). However, PM10 and PM2.5
consist of various substances besides AD. Light detection and ranging (LIDAR) systems can selectively
measure the quantity of AD particles to distinguish non-spherical airborne particles from spherical
airborne particles. The objective of this study was to investigate the relationship between pulmonary
function in adult asthma patients and AD using LIDAR data.
Methods: Subjects were 231 adult asthma patients who had their morning peak expiratory flow (PEF)
measured from March to May 2012. A linear mixed model was used to estimate the association of PEF
with sand dust particles detected by LIDAR.
Results: Increases in the interquartile range of AD particles (0.018 km
1) led to changes in PEF of
0.42 L/
min (95% confidence interval [CI],
0.85 to 0.01). An increase of 11.8 mg/m3 in suspended particulate
matter and 6.9 mg/m3 in PM2.5 led to decreases of
0.17 L/min (
0.53 to 0.21) and 0.03 L/min (
0.35 to
0.42), respectively. A heavy AD day was defined as a day with a level of AD particles >0.032 km
1, which
was the average plus one standard deviation during the study period, and six heavy AD days were
identified. Change in PEF after a heavy AD day was
0.97 L/min (
1.90 to
0.04).
Conclusions: Heavy exposure to AD particles was significantly associated with decreased pulmonary
function in adult asthma patients.