چکیده (انگلیسی):

Objective: To assess the effect of intrathecal Bupivacain–Lidocaine combination at different
doses of Lidocaine (6 and 12 mg) on the onset and recovery of anesthesia.
Methods: Ninety patients who were scheduled for elective lower abdominal surgery were randomly
allocated into three equal groups: Group I; 30 patients received 1.5 mL hyperbaric 0.5%
Bupivacaine + 0.6 mL saline. Group II; 30 patients received 1.5 mL hyperbaric 0.5%
Bupivacaine + 0.6 mL 1% Lidocaine [6 mg] mixed. Group III; 30 patients received 1.5 mL hyperbaric
0.5% Bupivacaine + 0.6 mL 2% Lidocaine [12 mg]. Peak sensory block level, time to peak
sensory block, times to two-segment, S2 regressions from peak sensory block, motor blocks at peak
sensory block and total motor block duration, post anesthesia care unit stay time and analgesia time
were measured.
Results: The median height of peak sensory block in Group III was higher than in Groups I or II.
Times to two-segment and S2 regressions from peak sensory block, motor block duration and
PACU time were significantly reduced in Group II compared to Group I and III. No patient
required general anesthesia. No patients experienced postdural puncture headache or TNS.
Conclusions: Lidocaine 1% (6 mg) mixed to spinal 1.5 mL hyperbaric 0.5% Bupivacaine (7.5 mg)
can shorten the duration of Bupivacaine spinal anesthesia, provide more rapid recovery from the spinal anesthesia compared to the same dose of 0.5% Bupivacaine (7.5 mg) alone or the same dose
of 0.5% Bupivacaine (7.5 mg) mixed with 0.6 mL 2% Lidocaine (12 mg).