چکیده (انگلیسی):

Objective: The reproductive performance of women with polycystic ovaries (PCO) with
regular ovulatory menstrual cycles undergoing in vitro fertilization and intra-cytoplasmic
sperm injection (IVF/ICSI) treatment has not been well described. This study aimed to
investigate the outcome of IVF/ICSI in ovulatory women with PCO.
Methods: A retrospective cohort study of women aged
42 years with infertility and
regular ovulatory menstrual cycles who underwent their first IVF/ICSI cycle using the
long down regulation protocol at IVF Australia-EAST in Sydney between 2000 and 2011.
A pre-treatment baseline transvaginal pelvic ultrasound (TVS) had been performed by a
single tertiary level diagnostic ultrasound center. Patients were divided into either group
NO (normal ovaries) or group PCO according to the pre-treatment TVS. The primary
outcome measure was live birth rate per patient.
Results: A total of 200 patients (135 in group NO and 65 in group PCO) were included
in the data analysis. There was no difference in live birth rate per patient between the two
groups (25.2% vs 26.2%) with both raw (OR [95% CI] = 1.05 [0.54–2.07]) and logistic
regression adjusted (for maternal age) (Adjusted OR [95% CI] = 0.99 [0.50–1.98]) data.
Conclusions: The presence of PCO in ovulatory women did not adversely affect IVF/
ICSI outcome at our unit. However, the results are not conclusive and further large, welldesigned
prospective cohort studies are required in order to confirm our findings.