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تاریخ امروز
پنج شنبه, ۳۱ مرداد

درمان جراحی اورژانسی پانکراتیت حاد پیچیده بعد از پیوند کلیه پس زده شده ی حاد: گزارش مورد و بررسی متون

Emergency surgical treatment of complicated acute pancreatitis after kidney transplantation with acute rejection: Case report and literature review

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ورودعضویت
اطلاعات مجله Annals of Medicine and Surgery www.annalsjournal.com
سال انتشار 2016
فرمت فایل PDF
کد مقاله 12046

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چکیده (انگلیسی):

Introduction: Acute pancreatitis is a rare but frequently fatal complication in patients following kidney
transplantation. The first case of acute pancreatitis in patients following a kidney transplant was
described by Starzl in 1964. The incidence of acute pancreatitis is stated at between 1 and 5%. The
mortality rate amongst these patients reaches as high as 50e100%.
Presentation of case: Here we present a case of acute pancreatic abscess in a caucasian female e shortly
following a kidney transplant complicated by the development of acute rejection, in which immunosuppressant
therapy is a potential etiological agent. Emergency surgical treatment was indicated, which
included drainage of the abscesses irrigation of the abdominal cavity. Immunosuppressive medication
was considered a possible etiological factor, and as a result administration of tacrolimus and mycophenolate
mofetil was discontinued. This was successful and three months later, diagnostic rebiopsy of
the graft was performed without signs of rejection.
Discussion: The etiology of this illness is multifactorial. The clinical manifestation of acute pancreatitis in
patients following kidney transplantation is the same as in the remainder of the population. However, in
patients following transplantation with long-term immunosuppression, it usually manifests a more rapid
development and a more severe, frequently fatal course.
Conclusions: With regard to the patient's comorbidities, early surgical therapy was indicated e drainage
and closed lavage and immunosuppressive medication as a suspected tobe ethiological factor was discontinued.
This course of treatment led to a complete recovery with preservation of good function of the
cadaverous kidney

کلمات کلیدی مقاله (فارسی):

پانکراتیت حاد، پیوند کلیه، درمان با غیر فعال کننده های سیستم ایمنی

کلمات کلیدی مقاله (انگلیسی):

Acute pancreatitis, Renal transplantation, Immunosuppressant therapy

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