چکیده (انگلیسی):

Background/Objective: Core needle biopsy (CNB) was widely used in the diagnosis
of ultrasound-detectable breast lesions. We aimed at assessing the diagnostic performance
differences between 14- and 16-gauge ultrasound-guided core biopsies.
Methods: This retrospective study enrolled patients receiving CNB from January 2001 to
December 2007. The results of 14- and 16-gauge breast CNBs were compared with pathology
reports of open surgical biopsy (OSB).
Results: A total of 1024 paired CNB and OSB results were obtained from 1732 CNB procedures in
1630 patients.Those CNB results reached 92.9% sensitivity, 99.7% specificity, 5.96% underestimation,
and 94.8% accuracy rates. There was no difference in sensitivity (p Z 0.17) or specificity
(p Z 0.38) between 14- and 16-gauge needles. However, better overall accuracy
(p Z 0.02), less underestimation (p < 0.001), and lower false-negative (p Z 0.02) rates were
found for the 14-gauge CNB.
Conclusion: Regarding accuracy and underestimation rates, a 14-gauge needle is preferred to
a 16-gauge one in ultrasound-guided biopsies.