چکیده (انگلیسی):

Follicular thyroid carcinoma (FTC) with sternum metastasis is rarely reported.
Conservative treatments always result in a poor prognosis. We report two cases of FTC presenting
with a large symptomatic solitary metastatic lesion in the sternum. Surgical intervention included
total thyroidectomy, combined with wide composite resection of the sternal manubrium, as well
as the adjacent clavicular head and ribs. A large defect with exposed pericardium and great
vessels was found post resection in both cases. Because the ipsilateral vessels were sacrificed,
a contralateral extended pedicled pectoralis major adipofascial flap was designed and transposed
to cover the underlying vital organs. The patients received both adjuvant I-131 and radiotherapy
postoperatively. The treatment was uneventful, and the patients are well and
asymptomatic 5 years after the treatment. Wide composite resection and appropriate adjuvant
therapies may offer a survival benefit in patients with advanced FTC with sternum metastasis.