چکیده (انگلیسی):

Background: This study compared the resistance of glued versus stapled anastomosis
of the colon to intraluminal pressures at different times during healing.
Methods: Forty seven female domestic pigs, mean weight of 30.7 kg, were used. Maximum
physiological luminal pressures, i.e. the pressure resisted by a catheter inserted into the intestinal
lumen via a puncture without it being released and without injury to the surrounding intestinal
wall, was performed in 5 control animals. The remaining 42 animals were divided into
3 groups of 14 animals each based on time from anastomosis construction. Each group was
divided into 2 subgroups with stapled or glued anastomoses. Intraluminal pressure was
measured on the first, third, and fifth day post-surgery.
Results: The maximum pressures resisted by anastomoses were significantly higher than the
physiological pressures in all groups. At all time points, stapled anastomoses resisted higher
intraluminal pressures than glued ones. However, glued anastomoses resisted pressures significantly
higher than physiological pressure. As healing advanced, glued anastomoses neared the
resistance to intraluminal pressures of stapled anastomoses.
Conclusion: Healing with absorbable synthetic glue was as good as with staples. Glued anastomoses
resisted pressures that were statistically significantly higher than physiological intraluminal
colon pressures but lower than stapled ones.