چکیده (انگلیسی):

Due to the high prevalence of food allergic diseases globally there are increasing demands in clinical
practice for managing IgE-mediated conditions. During the last decade, component resolved diagnostics
has been introduced into the field of clinical allergology, providing information that cannot be obtained
from extract-based tests. Component resolved data facilitate more precise diagnosis of allergic diseases
and identify sensitizations attributable to cross-reactivity. Furthermore it assists risk assessment in
clinical practice as sensitization to some allergenic molecules is related to persistence of clinical
symptoms and systemic rather than local reactions. The information may also aid the clinician in prescription
of oral immunotherapy (OIT) in patients with severe symptoms, and in giving advice on food
allergen avoidance or on the need to perform food challenges. The use of allergen components is rapidly
evolving and increases our possibility to treat food allergic patients with a more individual approach.
Using molecular allergology, we can already now better diagnose, prognose and grade the food allergy. In
summary, daily routine molecular allergy diagnostics offers a number of benefits that give us a higher
diagnostic precision and allow for better management of the patient.
Copyright © 2016, Japanese Society of Allergology.